This 2025 guide answers a common question: Do I need Yellow Fever Vaccine for Peru? It also explains how to get vaccinated in Lima and Arequipa.

If you’re planning to explore the Amazon Rainforest, hike the Inca Trail, or visit places like Cusco and Lake Titicaca, this is an experience you have to try at least once in your life. But before you go, make sure to prepare for travel challenges. Booking your flights or understanding the EasyJet cancellation policy that might affect your plans.
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Yellow Fever is a dangerous disease spread by mosquito bites. The vaccine protects you. Many countries ask for proof of vaccination. Airlines may deny boarding if you don’t have it. You must get the shot at least 10 days before your flight.
Other health concerns in Peru include hepatitis A, typhoid, tetanus, polio, rubella, and mumps. In some areas, you may also be at risk for malaria, dengue fever, and rabies.

Check Each Country’s Requirements
Check the vaccine rules for each country on your travel list. Use official sources like the CDC or WHO. Rules can change without notice.
Is Yellow Fever a Risk in All of Peru?
No. Cities and the Pacific coast are usually safe. Rural areas and the Amazon Rainforest have higher risk. Places like Iquitos, Cusco, and Lake Titicaca are included. These places are also at high altitude. Pack carefully and be alert.
To stay safe, wear insect repellent. Carry a portable mini fan. Cover your skin to avoid mosquito bites.
Yellow Fever Vaccine in Lima (NOT FREE)
Go to the health center at Jorge Chavez International Airport. Bring your passport. The vaccine is fast but costs money. Wait 10 days for it to work fully.
Yellow Fever Vaccine in Arequipa (FREE)
In Arequipa, you can get the vaccine for free. The steps take more time.
Take a taxi to Hospital Regional Honorio Delgado Espinoza. Make sure you’re at the correct hospital.
Finding the Vaccination Centre
Enter the car park. Turn left. Look for the building with baby posters. If you reach the far end of the hospital, turn back.
What to Do Inside
Ask if they give vaccines that day. Rules may change, but staff are usually helpful.
Go to the Caja (cashier) at the entrance. Buy the ‘Libro de vacunación’ or vaccine booklet. It costs about 10 soles or $3.
Get Vaccinated
Bring your passport and booklet. The nurse will help you fill it out. Then, you get your shot. You might feel sore or have a headache.
After the shot, go to the Mesa de Partes. Your booklet gets a final stamp. You’re done!

Other Health Tips for Traveling in Peru
Peru has many landscapes. Each place has its own health risks.
Altitude Sickness
Machu Picchu, Lake Titicaca, and Cusco are at high altitude. You may get altitude sickness. Symptoms include nausea, headache, or stomach pain. Take medications like acetazolamide. Drink water often. Use a refillable water bottle.
Infections and Illness
You can get sick in both cities and villages. Risks include hepatitis A, dengue fever, and typhoid. Drink clean water. Avoid risky food. Watch for signs of infection or illness.
Other Vaccines
Be protected against tetanus, polio, rubella, and mumps. Ask your doctor about pre-exposure prophylaxis for rabies. It helps if you’re near animals. Avoid bites and scratches.
Healthcare and Insurance
Get travel insurance for health before your trip. It helps with emergencies. Major cities like Lima and Cusco have hospitals. Rural areas may not.
How Long Does the Yellow Fever Vaccine Last?
The vaccine protects you for life. You don’t need a booster unless required. Always carry proof of vaccination.
Are There Side Effects?
Most people feel fine. You may get a sore arm, fever, or headache. These go away fast. Serious side effects are rare. See a doctor if symptoms worsen.
Who Should NOT Get the Vaccine?
Don’t get the vaccine if:
- You are younger than 9 months
- You have immune issues
- You are allergic to eggs or gelatin
- You are pregnant (check with your doctor)
Always check with your doctor first.
Can I Get Vaccinated Outside of Peru?
Yes. But it can cost more. In the U.S. or Europe, it may cost over $100. In Peru, it’s often cheaper. In Arequipa, it may be free.
Before you pack for Peru, get protected and stay informed. From jungle trails to mountain peaks, taking the right precautions will make your trip safer and more fun.
Ready to explore Peru with peace of mind? Start with your vaccine, then go plan your dream adventure today!
FAQ
If you’re staying in cities or coastal areas, maybe not. But if you’re going to the jungle, the Inca Trail, or nearby countries like Brazil, you likely will. Add the vaccine to your health prep and visa checklist.
The CDC recommends vaccines for hepatitis A, typhoid, yellow fever, tetanus, polio, rabies (for certain travelers), and MMR (measles, mumps, rubella). You may also consider malaria pills, especially for jungle areas. Always check with a travel doctor.
Children under 9 months should not get the Yellow Fever vaccine. Older adults above 60 may also face higher risk of side effects and should consult a doctor first.
Most side effects are mild, like fever, headache, or sore arm. Rarely, people may experience severe allergic reactions or neurological effects. These are uncommon. Discuss your health history with a doctor to decide if the vaccine is right for you.